Random thoughts of Terry Hamblin about leukaemia, literature, poetry, politics, religion, cricket and music.
Saturday, April 02, 2011
Gleevec for CLL
Mcl-1 is one of those anti-apoptotic proteins that belong to the bcl-2 family. It may well be the most important in CLL. A paper from Liverpool has demonstrated that c-Abl is involved in the up-regulation of Mcl-1 in CLL which suggests that Imatinib (Gleevec) might have a role in its management.