Wednesday, April 02, 2008

FISH and mutations



I have recently been asked whether del 11q is also influenced by the mutational status of IgVH genes. As you can see by these two survival curves, the answer is yes. I had not asked our data the question before, but the answer is clearly that for untreated patients the IgVH mutations trumps FISH. It ought to be publicised amongst oncologists because not a lot of people know this.

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