mutations of mortality

Random thoughts of Terry Hamblin about leukaemia, literature, poetry, politics, religion, cricket and music.

Wednesday, October 19, 2011

John 7:21-24. Set in their ways

›
Jesus said to them, “I did one miracle, and you are all amazed. Yet, because Moses gave you circumcision (though actually it did not come fr...
Tuesday, October 18, 2011

The genetics of CD38

›
Human CD38, located on the short arm of chromosome 4 (4p15), exhibits a number of unique features. First, the gene is relatively large, with...
4 comments:

Cutaneous Richter Syndrome

›
A paper in the Journal of the American Academy of Dermatology reports three cases of what they call cutaneous Richter syndrome. Case 1 A 74-...

John 7:20. The word not the wonder.

›
"You are demon-possessed," the crowd answered, " who is trying to kill you." This was a common accusation of the Jews ab...

A randomized trial of FA v F.

›
The Lancet Oncology reports and randomized phase 3 trial comparing fludarabine plus alemtuzumab with fludarabine alone in relased or refract...

Blowing our own trumpet

›
I had my first dose of my second course of my third line of chemotherapy this morning. Once again I was impressed by the set-up at the Royal...
Monday, October 17, 2011

The role of CD38 in affecting CLL migration

›
In vitro activation of CD38 caused by stimulating mAbs induces a portion of the CLL clone (10%-30%) to proliferate, giving rise to an immun...
10 comments:

Health update

›
I have a week off chemotherapy and I am feeling better. Last week we had some sunshine and I was able to go for a walk on the beach at respe...
2 comments:

CD38 and the BCR

›
Clones with higher numbers of CD38+ cells are generally those more responsive to BCR signaling in vitro, whereas CD38− clones are generally ...

What do we have but the Bible?

›
There is an extreme view of the origin of the gospels contaminated by the German higher critics of the nineteenth century, that holds that t...
2 comments:

John 7:19. Falling short.

›
"Has not Moses given you the law? Yet not one of you keeps the law. Why are you trying to kill me?” The inadequacy of the Law; it point...
Sunday, October 16, 2011

Royal Wooton Bassett

›
In a moving ceremony this afternoon the small town of Wooton Bassett received the Letters patent to be able to prefix the town's name wi...

Model of role of CD38

›
CD38+ CLL cells are more sensitive to chemokine (CXCL12) signals, with a higher likelihood to home to lymphoid tissues than the CD38− cells....

John 7:18. Content to be second

›
Whoever speaks on their own does so to gain personal glory, but he who seeks the glory of the one who sent him is a man of truth; there is n...
Saturday, October 15, 2011

CD38 as a marker in CLL

›
Like somatic mutations of IGHV, CD38 expression identifies two subgroups of CLL patients with different clinical outcomes; this distinction ...

Which is the best hospital in America?

›
Which are the best hospitals in America? Most people who make a judgement would pick on the famous ones like: MD Anderson, Duke, Mass Genera...
1 comment:

John 7:17 Doing God's will

›
Anyone who chooses to do the will of God will find out whether my teaching comes from God or whether I speak on my own. Being a Christian is...
1 comment:
Friday, October 14, 2011

Biology of CD38

›
Although originally defined as a T-cell activation molecule, CD38 expression is found on other cell lineages. Within the B-cell compartment,...

More persecution of Christians

›
From Barnabas Trust A young Pakistani Christian man was shot dead in a violent Muslim takeover of land allocated to a Christian village by t...

CD38 - a review

›
In the September issue of Blood is a useful review of CD38 by Fabio Malavasi from Turin. I will be taking it to pieces in the next few days ...
‹
›
Home
View web version

About Me

Terry Hamblin
Born in Worcester, England 1943; school at Farnborough, Hampshire 1954-62; University 1962-7 and junior doctor posts 1967-74 in Bristol; Consultant Haematologist Bournemouth 1974-2003; Professor of Immunohaematology Southampton 1986 to present. Honorary Consultant Haematologist Kings College Hospital, London, 2004-present. After 5 years of working part time researching, writing, reviewing, editing, speaking, sitting on committees, advising, answering questions and thinking, I now think of myself as fully retired apart from my role as Editor in Chief of the medical journal Leukemia Research. I was awarded the Binet-Rai medal for outstanding research in CLL in 2002 and this has been my most sucessful area of research, but I have also made important contributions in the fields of apheresis, stem cell transplantation, myeloma, myelodysplastic syndrome, antibody therapy, cytokine therapy and DNA vaccines. I was once mascot for Aldershot Town Football. Club. Married to Diane for 44 years. Four children, Karen, Richard, Angela and David.
View my complete profile
Powered by Blogger.