tag:blogger.com,1999:blog-19490962.post7953280314152479249..comments2023-12-10T10:06:41.979+00:00Comments on mutations of mortality: The kinetics of MRDTerry Hamblinhttp://www.blogger.com/profile/06346629921055055879noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-19490962.post-45172589176951554522011-12-01T13:01:46.676+00:002011-12-01T13:01:46.676+00:00Yes, that's how I understand it.Yes, that's how I understand it.Terry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-73927472162127865322011-12-01T12:02:55.111+00:002011-12-01T12:02:55.111+00:00Intuitively, it seems to me that individual cells ...Intuitively, it seems to me that individual cells would divide at the same rate whether they are one of a very small number of cells or of one of a large number of cells. Which would mean that the total bulk of a small number of cells in an MRD neg state would still take longer to reach relapse than a normal CR or a partial response.<br /><br />Is that about it, Doc?<br /><br />As I recall, you wrote somewhere once that all responses in cll are really partial responses, as there is always residual disease.<br /><br />So, essentially, this study is just affirming your view, I would think.Burkenoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-56421413596276171512011-12-01T09:40:26.637+00:002011-12-01T09:40:26.637+00:00Not reported in the abstractNot reported in the abstractTerry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-47559102645857465752011-12-01T07:25:45.091+00:002011-12-01T07:25:45.091+00:00Were any comparisons made of MRD kinetics with the...Were any comparisons made of MRD kinetics with the lymphocyte doubling times of patients before treatment?Richardnoreply@blogger.com