tag:blogger.com,1999:blog-19490962.post429621400906090006..comments2023-12-10T10:06:41.979+00:00Comments on mutations of mortality: My weekTerry Hamblinhttp://www.blogger.com/profile/06346629921055055879noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-19490962.post-75034819914470873802008-05-06T22:41:00.000+01:002008-05-06T22:41:00.000+01:00There is nothing to be lost by adding rituximab, b...There is nothing to be lost by adding rituximab, but bulky nodes are often best treated by adding high dose steroids.Terry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-31744771532500719272008-05-06T21:12:00.000+01:002008-05-06T21:12:00.000+01:00Dear Prof HamblinThis is a clinical query hence I ...Dear Prof Hamblin<BR/>This is a clinical query hence I have placed the comment after a more clinical post.<BR/>A 70y old Dx CLL on LN biopsy (presented to ENT) Dec 07, Lymphocyte count 6, normal Hb and Plt, immuno on PB CLL score 5/5, BM shows t(1;16) and del(6)(q), requires treatment by March 08 for increasingly bulky cervial LN, with generalised LN on radiology, responds within 1wk of first FC, but glands back up two week later. In your opinion would adding R be sufficient, or is there a better alternative?<BR/>Many ThanksAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-63894911036480938382008-05-02T23:13:00.000+01:002008-05-02T23:13:00.000+01:00It sounds as though you had a nice, full week.I al...It sounds as though you had a nice, full week.<BR/><BR/>I also had a full week. I went to the emergency room on Saturday because of a suddenly-worseing lung/sinus infection. I get blood drawn and have a chest X-ray. I wait from 8:00 pm until 2:00 am without seeing a doctor. I go home.<BR/><BR/>I got a prescription for antibiotic from the onc doc on Monday. I flew down to see my CLL doc on Tuesday. Spent day there. Miserable from cold/infection or whatever it is. <BR/><BR/>Try to work a bit on Wednesday and Thursday. Woke up on Friday feeling not right. Debating whether to go to the ER again to get another chest X-ray to see if something is growing in my lungs. <BR/><BR/>Research a bit on the net for latest developments in CLL. Nothing to speak of. Lots of nibbling at the margins, I guess you'd call it. Seems like better treatments are a decade or more away. Good, long-term career for CLL docs I think.<BR/><BR/>Call lawyer to make appointment to update trust/will etc. I grow increasingly concerned about what is going on with me. Discuss with wife funeral plans and estate matters.<BR/><BR/>Prepare for next trip to oncologist on Monday. Undecided on next treatment because there are so few effective treatments out there for high-risk CLL. <BR/><BR/>That was my week.Anonymousnoreply@blogger.com