tag:blogger.com,1999:blog-19490962.post3127620656493899836..comments2023-12-10T10:06:41.979+00:00Comments on mutations of mortality: Should I go for a transplant?Terry Hamblinhttp://www.blogger.com/profile/06346629921055055879noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-19490962.post-91250540592310919972009-02-02T21:31:00.000+00:002009-02-02T21:31:00.000+00:00Dr. Hamblin,Do patients who are contemplating a RI...Dr. Hamblin,<BR/><BR/>Do patients who are contemplating a RIC transplant, who have had blood product transfusions (either whole blood or plasma) run greater risk of failure and would this be time dependent?<BR/><BR/>WayneWaynehttps://www.blogger.com/profile/12333087913528941756noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-34321529129037197492009-02-01T03:44:00.000+00:002009-02-01T03:44:00.000+00:00I found Dr. Hamblin's post to be very easy to foll...I found Dr. Hamblin's post to be very easy to follow. Sometime you cannot 'dumb down' a vital topic such as this. <BR/><BR/>One of my complaints about telephone educational presentations or live presentations with Q and As is that they just go over the same old, basic territory over and over again.<BR/><BR/>This is because most attendees seem to go to these without doing any research, even with their CLL doctors.<BR/><BR/>There is NO FORUM to ask tough, detailed, complex questions about things as to what drives CLL proliferation, how new drugs are expected to work, and how to make decisions about treatment with a plethora of information concerning prognostic indicators.<BR/><BR/>I do value Dr. Hamblin's blog and columns elsewhere, where I can at least ask these types of questions.<BR/><BR/>As far as the topic of SCTs go, this highlights the dilemma that CLL patients are all to often faced with. Trying to make a life and death decision with incomplete information is cruel and unusual punishment, in my opinion.<BR/><BR/>But this is the burden we all face, sadly.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-86410724263081451622009-01-30T10:26:00.000+00:002009-01-30T10:26:00.000+00:00David, I am afraid there was no analysis of age in...David, I am afraid there was no analysis of age in the paper.<BR/><BR/>Anonymous, Sorry it was too technical, but it was a very technical paper. My next blog will look at a simiular paper and I will try to make it more readable.Terry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-45537298636556769142009-01-29T01:10:00.000+00:002009-01-29T01:10:00.000+00:00Dr. H,Perhaps it was me, but I found this to be ve...Dr. H,<BR/><BR/>Perhaps it was me, but I found this to be very confusing. It was definitely not up to your usual qualities of explanation.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-89674863503320504962009-01-28T23:07:00.000+00:002009-01-28T23:07:00.000+00:00Hi Terry.Thank you for your post. It comes at a ti...Hi Terry.<BR/><BR/>Thank you for your post. It comes at a time when I am grappling with the question of transplant and timing, if and when; the latest post on my blog details my visit to the NCI to discuss a clinical trial in which Campath would have been one of the randomized options for controlling GVHD.<BR/><BR/>A question: The median age of the 62 patients was 53 (which I will be this year) and those transplanted ranged in age from 34-64. Was there anything in the retrospective that provided useful information as to success by age or age group? The conventional wisdom is that the younger you are the better, but I would be curious to know if there are any hard facts on age as a factor in transplant. <BR/><BR/>DavidDavid Arensonhttps://www.blogger.com/profile/13876562687586184006noreply@blogger.com