tag:blogger.com,1999:blog-19490962.post116352509883063775..comments2023-12-10T10:06:41.979+00:00Comments on mutations of mortality: Del 17pTerry Hamblinhttp://www.blogger.com/profile/06346629921055055879noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-19490962.post-1165313286452734222006-12-05T10:08:00.000+00:002006-12-05T10:08:00.000+00:00Del17p is usually monoallelic. Do you agree? If it...Del17p is usually monoallelic. Do you agree? If it is monoallelic,is the second allele always mutated?<BR/>Does del17p always mean lack of p53 or only in the majority of cases? <BR/><BR/>Thanks for your excellent web page.<BR/><BR/>MartinaAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-1164254446656090962006-11-23T04:00:00.000+00:002006-11-23T04:00:00.000+00:00I understand that del 11q is also harder to treat....I understand that del 11q is also harder to treat. Is Rituxan an option for del 11q?Brian Koffmanhttps://www.blogger.com/profile/13250684684103918493noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-1163707411729802822006-11-16T20:03:00.000+00:002006-11-16T20:03:00.000+00:00It's done on a blood test.It's done on a blood test.Terry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-1163691608506080652006-11-16T15:40:00.000+00:002006-11-16T15:40:00.000+00:00How do you test for the 17p deletion? On bone marr...How do you test for the 17p deletion? On bone marrow sampling or by a blood test?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-19490962.post-1163575433770213612006-11-15T07:23:00.000+00:002006-11-15T07:23:00.000+00:00No, it is part of the short arm, but more than jus...No, it is part of the short arm, but more than just the p53 gene. But you need full karyotyping to know that. FISH only looks at the p53 gene.Terry Hamblinhttps://www.blogger.com/profile/06346629921055055879noreply@blogger.comtag:blogger.com,1999:blog-19490962.post-1163556932574213832006-11-15T02:15:00.000+00:002006-11-15T02:15:00.000+00:00Dr. Hamblin,Is the entire short arm of p17 deleted...Dr. Hamblin,<BR/><BR/>Is the entire short arm of p17 deleted, or is the p53 gene just one of many locations (or loci) on that arm?<BR/><BR/>Thanks for you help to all CLLers.<BR/><BR/>GeorgeAnonymousnoreply@blogger.com